TrimRx offers two GLP-1 medicines: semaglutide and tirzepatide. Both are weekly injections that help you feel full sooner and eat less. Here is how they differ, in plain words.
Large studies of the brand-name medicines showed strong results when combined with diet and exercise:
These studies used the brand-name medicines. TrimRx provides compounded versions, made by a state-licensed pharmacy for each patient. Compounded medicines are not FDA-approved products, so your provider guides your dose and checks how you are doing.
| Semaglutide | Tirzepatide | |
|---|---|---|
| How it works | GLP-1 | GLP-1 + GIP |
| How you take it | Once-a-week injection | Once-a-week injection |
| Brand names | Wegovy, Ozempic | Zepbound, Mounjaro |
| TrimRx first month | $199 ($179 with current offer) | $349 ($279 with current offer) |
| TrimRx after | $299 a month | $399 a month |
Both medicines have similar side effects. The most common, according to the Wegovy and Zepbound labels, are:
These often ease as your body gets used to the medicine. Starting at a low dose and going up slowly helps. Tell your provider if side effects bother you.
Do not use either medicine if you or a family member has had medullary thyroid cancer or a condition called MEN 2, if you have had a serious allergy to the medicine, or if you are pregnant or planning a pregnancy.
Your TrimRx provider will help you decide, based on your health, your goals and your budget. Semaglutide costs less per month. Tirzepatide acts on two hormones and showed larger average weight loss in studies of the brand-name medicines.
Learn more: TrimRx reviews, how TrimRx works and TrimRx vs Hims, Ro and Henry Meds.
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Semaglutide acts like one gut hormone (GLP-1). Tirzepatide acts like two (GLP-1 and GIP). Both are weekly injections that help you feel full sooner.
In the SURMOUNT-5 study of the brand-name medicines, tirzepatide led to about 20% weight loss and semaglutide about 14% over 72 weeks.
The most common are nausea, diarrhea, vomiting and constipation. They often ease as your body adjusts.
